Longitudinal automated assessments of myocardial strain from cine MR in cancer patients receiving cardiotoxic chemotherapy
نویسندگان
چکیده
Background The use of chemotherapy for the treatment of cancer is associated with cardiovascular injuries and is most commonly monitored with assessments of left ventricular ejection fraction (EF) [1]. Often, EF changes are detected quite late; myocardial strain may identify early, subclinical changes in myocardial injury prior to a decline in EF. Recently, it has been possible to measure myocardial strain directly from cine images without the need for tagged images. We performed a longitudinal study to determine (1) the feasibility of assessing myocardial strain from cine images with automated analysis and (2) if subclinical changes in myocardial contractility can be observed with this new technique in patients receiving cardiotoxic chemotherapies.
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